Ningegowda, Raghu’s team published research in Chemical Data Collections in 2020-08-31 | 2905-54-6

Chemical Data Collections published new progress about Benzoic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 2905-54-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H6Cl2O2, COA of Formula: C8H6Cl2O2.

Ningegowda, Raghu; Chandrashekharappa, Sandeep; Singh, Vinayak; Mohanlall, Viresh; Venugopala, Katharigatta N. published the artcile< Design, synthesis and characterization of novel 2-(2,3-dichlorophenyl)-5-aryl-1,3,4-oxadiazole derivatives for their anti-tubercular activity against Mycobacterium tuberculosis>, COA of Formula: C8H6Cl2O2, the main research area is dichlorophenyl aryl oxadiazole preparation antitubercular.

A novel series of 2-(2,3-dichlorophenyl)-5-aryl-1,3,4-oxadiazole derivatives I [R = 3-BrC6H4, 2,3-di-ClC6H3, isoxazol-5-yl, etc.] was synthesized by three-step chem. synthesis and purified by column chromatog. method. The antimycobacterial activity of the title compounds I was evaluated against Mycobacterium tuberculosis H37RvMa strain (ATCC 27294) by the broth micron-dilution method. The title compound I [R = 3-NO2-4-FC6H3] emerged as a promising anti-TB agent at 62.5μg/mL.

Chemical Data Collections published new progress about Benzoic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 2905-54-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H6Cl2O2, COA of Formula: C8H6Cl2O2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics