Parada, Luz Karime Luna; Kouznetsov, Vladimir V. published the artcile< 5-chloro-8-{[1-(2-chlorobenzyl)-1H-1,2,3-triazol-4-yl]methoxy}quinoline>, Safety of 1-Chloro-2-(chloromethyl)benzene, the main research area is triazolyl quinoline hybrid preparation; alkyne azide dipolar cycloaddition copper catalyst.
The title quinoline derivative, 5-chloro-8-{[1-(2-chlorobenzyl)-1H-1,2,3-triazol-4-yl]methoxy}quinoline, was synthesized in a common three-step procedure from 5-chloro-8-hydroxyquinoline using O-propargylation reaction/copper-catalyzed 1,3-dipolar cycloaddition sequence. The hybrid obtained could be an interesting model for antifungal bio-essays or a suitable precursor in the synthesis of more complex triazolyl-quinoline hybrids, potential pharmacol. agents.
Molbank published new progress about 1,3-Dipolar cycloaddition reaction. 611-19-8 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H6Cl2, Safety of 1-Chloro-2-(chloromethyl)benzene.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics