Ruan, Zhixiong; Huang, Zhixing; Xu, Zhongnan; Mo, Guangquan; Tian, Xu; Yu, Xi-Yong; Ackermann, Lutz published the artcile< Catalyst-Free, Direct Electrochemical Tri- and Difluoroalkylation/Cyclization: Access to Functionalized Oxindoles and Quinolinones>, Synthetic Route of 17082-09-6, the main research area is acrylamide fluoroalkyl sodium sulfinate electrochem trifluoroalkylation difluoroalkylation cyclization; fluoroalkylated oxindole electrochem preparation; quinolinone fluoroalkylated electrochem preparation.
The catalyst-free electrochem. di- and trifluoromethylation/cyclization of N-substituted acrylamides was realized under external oxidant-free conditions. The strategy provides expedient access to fluoroalkylated oxindoles, e.g., I, and 3,4-dihydroquinolin-2(1H)-ones with ample scope and broad functional group tolerance by mild, direct electrolysis of sodium sulfinates in an undivided cell. Detailed mechanistic studies provided strong support for a SET-based reaction manifold.
Organic Letters published new progress about Acrylamides Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 17082-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H7ClO, Synthetic Route of 17082-09-6.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics