Jiang, Quanbin; Li, Huimin; Zhao, Xiaodan published the artcile< Catalytic Electrophilic Thiocarbocyclization of Allenes>, Electric Literature of 128-09-6, the main research area is indene sulfide preparation regioselective; allene sulfur reagent electrophilic thiocarbocyclization selenide catalyst.
An efficient approach via catalytic electrophilic thiocarbocyclization of allenes (3-R-4-R1C6H4)(R2)C=C=CR3 (R = H, F; R1 = H, Me, Cl, F, CN; R2 = Me, Et, Ph; R3 = n-Pr, Ph, 2-methoxyphenyl, 4-bromophenyl, etc.) to construct indene-based sulfides I (R4 = n-Pr, hexyl, Ph, Bn, etc.) with excellent regioselectivities is disclosed. The reactions were carried out at low temperatures by selenide catalysis in the presence of TMSOTf. Not only electrophilic arylthio reagents II (R4 = Ph, 2-methylphenyl, 4-methylphenyl, 4-fluorophenyl, Bn) but also electrophilic alkylthio reagents II (R4 = n-Pr, hexyl, 3-methylbutyl, 3-chloropropyl) worked well under these conditions. Furthermore, the method could be applied to intermol. azidothiolation of allenes.
Organic Letters published new progress about Allenes Role: RCT (Reactant), RACT (Reactant or Reagent). 128-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C4H4ClNO2, Electric Literature of 128-09-6.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics