Safety of Thiophene-2-sulfonyl chlorideIn 2020 ,《Electrochemical Oxidation-induced Difunctionalization of Alkynes and Alkenes with Sulfonyl Hydrazides: Facile Access to β-Selenovinyl Sulfones and β-Ketosulfones》 was published in Asian Journal of Organic Chemistry. The article was written by Kong, Xianqiang; Yu, Ke; Chen, Qianjin; Xu, Bo. The article contains the following contents:
Herein, an efficient electrochem. oxidative selenosulfonylation of alkynes R1CCR2 (R1 = Et, Ph, naphthalen-2-yl, etc.; R2 = H, Me, Ph, etc.) and oxysulfonylation of alkenes R3CH=CH2 (R3 = H, 4-nitrophenyl, 3,4-dichlorophenyl, etc.) without use of metal catalysts were reported. This method provides a practical access to a wide range of β-(seleno)vinyl sulfones RS(O)2C(R2)=C(R1)SePh (R = Et, 4-chlorophenyl, thiophen-2-yl, etc.) and β-keto sulfones RS(O)2CH2C(O)R3. These reactions can tolerate various functional groups and be easily scaled-up. The results came from multiple reactions, including the reaction of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Safety of Thiophene-2-sulfonyl chloride)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Safety of Thiophene-2-sulfonyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics