Li, Lin; Li, Miao; Chi, Huiwei; Yang, Jichun; Li, Zhinian; Liu, Changling published the artcile< Discovery of flufenoxystrobin: Novel fluorine-containing strobilurin fungicide and acaricide>, HPLC of Formula: 35852-58-5, the main research area is flufenoxystrobin fluorine strobilurin preparation fungicide acaricide.
To discover new strobilurin analogs with high activity, a series of new fluorine-containing strobilurin derivatives were synthesized utilizing intermediate derivatization methods (IDM). The compounds were identified by 1H and 19F NMR, IR and elemental anal. Preliminary bioassays in greenhouse indicated that compounds (I) (SYP-3759, flufenoxystrobin) and (II) exhibited excellent fungicidal activities against Erysiphe graminis protecting wheat at 1.56 mg L-1 concentration and compounds 2a showed a moderately high acaricidal activity at 10 mg L-1. Field trials showed the fungicidal activities of compounds I and II is almost equivalent to that of pyraclostrobin, higher than that of triadimefon and the acaricidal activity of compound I is almost equivalent to that of pyidaben, but lower than that of fluacrypyrim. The preliminary mammalian toxicol. results showed compound I was a low-toxicity compound In conclusion compound I is a promising candidate for further development; mammalian toxicol. and ecotoxicol. with compound I are in progress.
Journal of Fluorine Chemistry published new progress about Acaricides. 35852-58-5 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H4ClF3O, HPLC of Formula: 35852-58-5.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics