Ma, Menglin; Xiang, Feng; Xin, Ying; Wang, Yuliang; Chen, Shuhua published their research in Sichuan Daxue Xuebao, Ziran Kexueban on February 29 ,2004. The article was titled 《Studies on synthesis of halogenated hydroxyl diphenyl ethers》.Reference of 2-Amino-2,4-dichlorodiphenyl ether The article contains the following contents:
Hydroxydiphenyl ethers were synthesized from halogenated phenol and dinitrochlorobenzene via modified Williamson etherification, reduction and diazotization. The modified Williamson etherification was performed by melting in a solvent free system to prepare substituted nitro-diphenyl ethers. The process for hydrolyzation of diazonium salt was improved by adjusting the acidity of the reaction. In the experiment, the researchers used many compounds, for example, 2-Amino-2,4-dichlorodiphenyl ether(cas: 56966-48-4Reference of 2-Amino-2,4-dichlorodiphenyl ether)
2-Amino-2,4-dichlorodiphenyl ether(cas: 56966-48-4) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.Reference of 2-Amino-2,4-dichlorodiphenyl ether
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics