Reference of Methyl 2-chloro-2-oxoacetateIn 2021 ,《Synthesis of Alkyl Fluorides by Silver-Catalyzed Radical Decarboxylative Fluorination of Cesium Oxalates》 was published in European Journal of Organic Chemistry. The article was written by Vincent, Emilie; Brioche, Julien. The article contains the following contents:
A combination of silver nitrate (AgNO3) catalyst and Selectfluor was found to perform radical deoxyfluorination of cesium oxalates derived from corresponding alcs. The reaction tolerates a wide range of functional groups and provides preferentially access to tertiary alkyl fluorides. The results came from multiple reactions, including the reaction of Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3Reference of Methyl 2-chloro-2-oxoacetate)
Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3) belongs to acyl chlorides. Lacking the ability to form hydrogen bonds, acyl chlorides have lower boiling and melting points than similar carboxylic acids. For example, acetic acid boils at 118 °C, whereas acetyl chloride boils at 51 °C. Like most carbonyl compounds, infrared spectroscopy reveals a band near 1750 cm−1.Reference of Methyl 2-chloro-2-oxoacetate
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics