Wu, Chao; Wang, Jiang; Zhang, Xumu; Zhang, Runtong; Ma, Baode published the artcile< Highly chemoselective hydrogenation of cyclic imides to ω-hydroxylactams or γ-hydroxyamides catalyzed by iridium catalysts>, Electric Literature of 118-45-6, the main research area is hydroxylactam chemoselective preparation; hydroxyamide chemoselective preparation; cyclic imide hydrogenation iridium catalyst.
Several novel ferrocene-based PNN ligands were prepared, which were found to be highly effective catalysts (TON up to 50 000) for the homogeneous hydrogenation of cyclic imides with iridium. The hydrogenation mode could be finely tuned by tiny changes in the ligands. Using this straightforward strategy, a plethora of ω-hydroxylactams I [R = H, 4-Cl, 5-Cl; R1 = Me, Ph, Bn, etc.] and ω-hydroxyamides, e.g., II with different functional groups were obtained in high yield.
Organic Chemistry Frontiers published new progress about Amides, hydroxy Role: SPN (Synthetic Preparation), PREP (Preparation). 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Electric Literature of 118-45-6.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics