Zhao, Yunlong; Liu, Chen-Fei; Lin, Leroy Qi Hao; Chan, Albert S. C.; Koh, Ming Joo published an article in Angewandte Chemie, International Edition. The title of the article was 《Stereoselective Synthesis of Trisubstituted Alkenes by Nickel-Catalyzed Benzylation and Alkene Isomerization》.COA of Formula: C7H6Cl2 The author mentioned the following in the article:
Herein, diastereo- and regioselective synthesis of trisubstituted alkenes via nickel-catalyzed benzylation and isomerization of terminal olefins with benzyl chlorides in presence of trimethylsilyl triflate and trimethylamine additives was described. Control experiments provided evidence for a mechanism involving branched-selective Heck-type benzylation that overrides substrate control, followed by trans-selective 1,3-hydrogen shift. The method represented a significant addition to the toolbox of reactions for the concise synthesis of unsaturated biol. active compounds In the experimental materials used by the author, we found 3-Chlorobenzylchloride(cas: 620-20-2COA of Formula: C7H6Cl2)
3-Chlorobenzylchloride(cas: 620-20-2) has been used in the reaction of 3-methoxybenzyl chloride and ethyl 4-bromobenzoate in pure water, using zinc dust and a Pd catalyst.COA of Formula: C7H6Cl2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics