Application of 56966-48-4On May 4, 1984 ,《The Halogen-activated Smiles rearrangement. 2》 appeared in Journal of Organic Chemistry. The author of the article were Schmidt, Diane M.; Bonvicino, Guido E.. The article conveys some information:
The cyclization of diaryl ethers I (R = H, R1 = Cl; R = Cl, R1 = H) with K2CO3/DMF gave phenoxazines II via the Smiles-rearranged intermediates III. III, isolated as the betaines, were cyclized to II. In the part of experimental materials, we found many familiar compounds, such as 2-Amino-2,4-dichlorodiphenyl ether(cas: 56966-48-4Application of 56966-48-4)
2-Amino-2,4-dichlorodiphenyl ether(cas: 56966-48-4) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.Application of 56966-48-4
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics