Chang, Suae-Chen; Gleicher, Gerald J. published the artcile< Attempt to observe neighboring group participation in hydrogen abstraction from β-(substituted phenyl)-ethyl bromides>, Synthetic Route of 16799-05-6, the main research area is hydrogen abstraction phenethyl bromide; mechanism hydrogen abstraction.
A series of β-(substituted phenyl)-ethyl bromides are reacted with bromotrichloromethane at 70°. Benzylic hydrogen abstraction comprises the only reaction. The exptl. ρ value for this process is -0.83 ± 0.02. A ρ value is calculated to have the range of -0.84 to -0.90. The negligible difference between these two ρ values is indicative of no anchimeric assistance in this reaction by the neighboring bromine atom under the conditions utilized.
Journal of Organic Chemistry published new progress about Abstraction reaction. 16799-05-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H8BrCl, Synthetic Route of 16799-05-6.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics