The author of 《Facile one-pot synthesis of diarylacetylenes from arylaldehydes via an addition-double elimination process》 were Chen, Jianyang; Zhang, Xuan; Wu, Jiajun; Wang, Rui; Lei, Chunlin; An, Yanan. And the article was published in Organic & Biomolecular Chemistry in 2021. Application of 620-20-2 The author mentioned the following in the article:
A practical one-pot protocol has been developed to synthesize diarylacetylenes ArCCAr1 (Ar = Ph, naphthalen-1-yl, furan-2-yl, etc.; Ar1 = Ph, 4-chlorophenyl, naphthalen-2-yl, etc.) from arylaldehydes ArCHO by treatment with 1-(arylmethyl)benzotriazoles I and LiN(SiMe3)2. The reaction proceeded through imine formation, Mannich-type addition and double elimination to deliver products in up to 99% yields with broad substrate scope. In addition, gram-scale synthesis of diarylacetylene (Ar = 4-bromophenyl, Ar1 = Ph) has been demonstrated. The experimental process involved the reaction of 3-Chlorobenzylchloride(cas: 620-20-2Application of 620-20-2)
3-Chlorobenzylchloride(cas: 620-20-2) has been used in the reaction of 3-methoxybenzyl chloride and ethyl 4-bromobenzoate in pure water, using zinc dust and a Pd catalyst.Application of 620-20-2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics