Jin, Xin; Cao, Jianguo; Zhao, Qingjie; Wang, Qi; Guo, Hongmei; Aisa, Haji Akber; Huang, Guozheng published their research in Journal of the Serbian Chemical Society in 2021. The article was titled 《Synthesis of new derivatives of alepterolic acid via click chemistry》.Computed Properties of C7H6BrCl The article contains the following contents:
In this article, 23 new derivatives of alepterolic acid combined with 1,2,3-triazole I (R = Ph, 2-methylphenyl, 4-fluorophenyl, etc.) were designed and synthesized by esterification and click chem. reaction in a fast, conventional and efficient way. All the products were obtained in good yields (72 to 97%). The use of the easily available reactants and the common reaction conditions furnish an efficient method for the synthesis of alepterolic acid derivatives I. The preparation of these compounds would enable further biol. evaluation in the future. In the experimental materials used by the author, we found 1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7Computed Properties of C7H6BrCl)
1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7) is a useful reagent for the preparation of panicinotam derivatives for use as anti-inflammatory agents or immunomodulators.Computed Properties of C7H6BrCl It can be synthesized by reacting 4-chlorobenzyl alcohol with bromodimethylsulfonium bromide (BDMS) It can also be synthesized by refluxing a mixture of 4-chlorobenzaldehyde, chlorotrimethylsilane, 1,1,3,3-tetramethyldisiloxane and lithium bromide.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics