Formula: C11H13ClO2On November 1, 2013 ,《Metal-Catalyzed Benzylic Fluorination as a Synthetic Equivalent to 1,4-Conjugate Addition of Fluoride》 appeared in Journal of Organic Chemistry. The author of the article were Bloom, Steven; Sharber, Seth Andrew; Holl, Maxwell Gargiulo; Knippel, James Levi; Lectka, Thomas. The article conveys some information:
We explore in detail the iron-catalyzed benzylic fluorination of substrates containing aromatic rings and electron-withdrawing groups positioned β to one another, thus providing direct access to β-fluorinated adducts. This operationally convenient process can be thought of not only as a contribution to the timely problem of benzylic fluorination but also as a functional equivalent to a conjugate addition of fluoride, furnishing products in moderate to good yields and in excellent selectivity. The experimental process involved the reaction of Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Formula: C11H13ClO2)
Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Formula: C11H13ClO2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics