Elrod, Lee Jr.; Spanton, Stephen G.; Cirovic, Mike; Shaffer, Dean I.; Golich, Timothy G.; Linton, Cathie L.; Vievia, Douglas R.; Kalaritis, Panos; Schmand, Horst published their research in Analytica Chimica Acta on August 2 ,1993. The article was titled 《Determination of 2-chloro-4,5-difluorobenzoic acid and related impurities by liquid chromatography》.Reference of 2-Chloro-3,4-difluorobenzoic acid The article contains the following contents:
2-Chloro-4,5-difluorobenzoic acid (CDFBA) and related impurities are determined using liquid chromatog. (LC). Separations are achieved using a reversed-phase isocratic system with an ion-pair reagent (tetrabutylammonium hydroxide). Unique isomeric impurities observed in com. produced CDFBA were isolated and identified by NMR and single crystal x-ray diffraction. The method has relative standard deviations of ±0.55% to ±1.26% for the CDFBA determination and from ±4.3% to ±12% for impurities below 0.3% in CDFBA. Impurities are determinable to at least 0.03% by weight The experimental part of the paper was very detailed, including the reaction process of 2-Chloro-3,4-difluorobenzoic acid(cas: 150444-93-2Reference of 2-Chloro-3,4-difluorobenzoic acid)
2-Chloro-3,4-difluorobenzoic acid(cas: 150444-93-2) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Reference of 2-Chloro-3,4-difluorobenzoic acid Organochlorine compounds have wide use in many applications, though some are of profound environmental concern, with TCDD being one of the most notorious.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics