Application In Synthesis of 3-Chloro-4-fluoronitrobenzeneOn March 31, 2019, Isaka, Masahiko; Yangchum, Arunrat; Supothina, Sumalee; Veeranondha, Sukitaya; Komwijit, Somjit; Phongpaichit, Souwalak published an article in Journal of Antibiotics. The article was 《Semisynthesis and antibacterial activities of nidulin derivatives》. The article mentions the following:
Derivatives of the fungal depsidone, nidulin, have been synthesized in order to evaluate the potential of the chem. skeleton as antibacterial agents. Alkylation, acylation, and arylation reactions of nornidulin underwent in a regioselective manner to predominantly produce 8-O-substituted derivatives Many of the semisynthetic derivatives showed more potent antibacterial activities than nidulin, In particular, 8-O-aryl ether derivatives displayed significant activities against Gram-pos. bacteria, including Methicillin-resistant Staphylococcus aureus. In the experiment, the researchers used 3-Chloro-4-fluoronitrobenzene(cas: 350-30-1Application In Synthesis of 3-Chloro-4-fluoronitrobenzene)
3-Chloro-4-fluoronitrobenzene(cas: 350-30-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Application In Synthesis of 3-Chloro-4-fluoronitrobenzene
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics