Lv, Yunhe; Han, Wanru; Pu, Weiya; Xie, Jinhui; Wang, Axue; Zhang, Mengyue; Wang, Jin; Lai, Junrong published an article in 2022. The article was titled 《Copper-catalyzed regioselective 1,4-sulfonylcyanation of 1,3-enynes with sulfonyl chlorides and TMSCN》, and you may find the article in Organic Chemistry Frontiers.Computed Properties of C4H3ClO2S2 The information in the text is summarized as follows:
A novel and practical copper-catalyzed reaction for the 1,4-sulfonylcyanation of 1,3-enynes under mild conditions was described. This protocol provided efficient and straightforward access to a variety of 5-sulfonylpenta-2,3-dienenitrile derivatives with excellent functional group tolerance and good regioselectivity from readily available 1,3-enynes and com. available sulfonyl chlorides and TMSCN. A mechanism involving sulfonyl and allenyl radical species was proposed. After reading the article, we found that the author used Thiophene-2-sulfonyl chloride(cas: 16629-19-9Computed Properties of C4H3ClO2S2)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Computed Properties of C4H3ClO2S2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics