《Reductive amination using cobalt-based nanoparticles for synthesis of amines》 was written by Murugesan, Kathiravan; Chandrashekhar, Vishwas G.; Senthamarai, Thirusangumurugan; Jagadeesh, Rajenahally V.; Beller, Matthias. Recommanded Product: 350-30-1 And the article was included in Nature Protocols on April 30 ,2020. The article conveys some information:
In this protocol, the preparation of carbon-supported cobalt-based nanoparticles as efficient and practical catalysts for synthesis of different kinds of amines by reductive aminations was described. Template synthesis of a cobalt-triethylenediamine-terephthalic acid metal-organic framework on carbon and subsequent pyrolysis to remove the organic template resulted in the formation of supported single cobalt atoms and nanoparticles. Applying these catalysts, structurally diverse benzylic, aliphatic and heterocyclic primary, secondary and tertiary amines, including pharmaceutically relevant products, starting from inexpensive and easily accessible carbonyl compounds with ammonia, nitro compounds or amines and mol. hydrogen were synthesized. To prepare this cobalt-based catalyst took 26 h, and the reported catalytic reductive amination reactions could be carried out within 18-28 h. The results came from multiple reactions, including the reaction of 3-Chloro-4-fluoronitrobenzene(cas: 350-30-1Recommanded Product: 350-30-1)
3-Chloro-4-fluoronitrobenzene(cas: 350-30-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Recommanded Product: 350-30-1
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics