Vijayakrishnan, Sriram’s team published research in ACS Catalysis in 2022 | CAS: 98019-65-9

4-Oxo-2-azetidinecarboxylic acid(cas:98019-65-9) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.Related Products of 98019-65-9 Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.

《Discovery of a Covalent Triazine Framework Photocatalyst for Visible-Light-Driven Chemical Synthesis using High-Throughput Screening》 was written by Vijayakrishnan, Sriram; Ward, John W.; Cooper, Andrew I.. Related Products of 98019-65-9 And the article was included in ACS Catalysis on August 19 ,2022. The article conveys some information:

Reported the discovery of a covalent triazine framework photocatalyst (CTF-2) for decarboxylative conjugate addition of a range of carboxylic acids under visible-light irradiation The decarboxylation reaction was coupled with a variety of other reactions, including metallaphotoredox arylation, alkylation, fluorination and dehydrogenative aniline synthesis. CTF-2 was prepared on a large scale and recycled without loss of catalytic efficiency for at least four cycles. To demonstrate application in pharmaceutical drug synthesis, synthesized (±)-rolipram in five steps from isovanillin using a CTF-2-catalyzed decarboxylative conjugate addition as the key step. In the experiment, the researchers used 4-Oxo-2-azetidinecarboxylic acid(cas: 98019-65-9Related Products of 98019-65-9)

4-Oxo-2-azetidinecarboxylic acid(cas:98019-65-9) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.Related Products of 98019-65-9 Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics