Amperayani, Karteek Rao; Parimi, Uma Devi published the artcile< Effect of silk strength by dietary supplementation of silk worm with 1,3,4-thiadiazoles, in silico and in vitro Bombyx mori DNA binding studies>, Product Details of C8H6ClN3S, the main research area is Bombyx silk strength feeding thiadiazole DNA binding.
In silico and in vitro DNA binding studies were carried out on silk worm DNA to determine the efficiency of 1,3,4-thiadiazoles (Th1-9) on Bombyx mori larvae during their 5th instar larval stage to increase the tensile strength, quality and quantity of biopolymer silk. These compounds were synthesized using ultrasonication method and supplied in ultra-dose as food supplement along with mulberry leaves to Bombyx mori and recorded the growth and other parameters of silkworm, cocoon parameters and mech. testing of silk filament. Tensile Strength, elongation and quantity of the silk was higher in larvae fed with synthesized compound in comparison with control larvae. This increase in strength and quality was due to the strong binding interactions of thiadiazoles moiety with silk worm DNA which was confirmed by higher binding energy values showed in In silco studies and DNA binding assay results.
Pharma Chemica published new progress about Binding energy. 70057-67-9 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H6ClN3S, Product Details of C8H6ClN3S.
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