《Catalytic enantioselective synthesis of tetrasubstituted chromanones via palladium-catalyzed asymmetric conjugate arylation using chiral pyridine-dihydroisoquinoline ligands》 was written by Baek, Doohyun; Ryu, Huijeong; Ryu, Ji Yeon; Lee, Junseong; Stoltz, Brian M.; Hong, Sukwon. Quality Control of (3-Fluorophenyl)boronic acid And the article was included in Chemical Science in 2020. The article conveys some information:
Highly enantioselective conjugate addition reactions of arylboronic acids to 2-substituted chromones catalyzed by palladium complexes with new chiral pyridine-dihydroisoquinoline (PyDHIQ) ligands was developed. These reactions provide highly enantioselective access to chromanones containing tetrasubstituted stereocenters. Various arylboronic acids and 2-substituted chromones were used in the catalytic reaction which afforded the chiral tetrasubstituted chromanones in good yields and excellent enantioselectivities (25 examples, up to 98% yields, up to 99% ee). The results came from multiple reactions, including the reaction of (3-Fluorophenyl)boronic acid(cas: 768-35-4Quality Control of (3-Fluorophenyl)boronic acid)
(3-Fluorophenyl)boronic acid(cas: 768-35-4) can be used to make novel liquid crystalline fluorobiphenylcyclohexenes and difluoroterphenyls by palladium-catalyzed cross-couplings also used in the synthesis of o-phenylphenols as potent leukotriene B4 receptor agonists.Quality Control of (3-Fluorophenyl)boronic acid
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics