The author of 《Metabolism of 2,3-, 2,6-, and 3,5-dichloronitrobenzene and the formation of a mercapturic acid from 2,3,4,5-tetrachloronitrobenzene in the rabbit》 were Bray, H. G.; James, Sybil P.; Thorpe, W. V.. And the article was published in Biochemical Journal in 1957. Safety of 2,4-Dichloro-3-nitrophenol The author mentioned the following in the article:
cf. C.A. 52, 16882f. The metabolism of 2,3-, 2,6-, and 3,5-dichloronitrobenzene has been studied in the rabbit. The main products excreted are phenols, conjugated with glucuronic and sulfuric acids, and dichloroanilines (2,3-dichloroaniline (acetyl and picrate derivatives), 4-amino-3,5-dichlorophenol, 3,5-dichloroaniline (acetyl derivative), 3,5,3′,5′-tetrachloroazoxybenzene, 2-amino-4,6-dichlorophenol, 4-amino-2,6-dichlorophenol). A small amount of a pyrocatechol derivative is probably formed from the 2,6-isomer. No mercapturic acids were detected in the urines. A mercapturic acid (N-acetyl-S-(2,3,4-trichloro-6-nitrophenyl)-L-cysteine) has been isolated from the urine of rabbits given 2,3,4,5-tetrachloronitrobenzene. The chief features of the metabolism of 19 chloromononitrobenzenes have been summarized and discussed. The experimental process involved the reaction of 2,4-Dichloro-3-nitrophenol(cas: 38902-87-3Safety of 2,4-Dichloro-3-nitrophenol)
2,4-Dichloro-3-nitrophenol(cas: 38902-87-3) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Safety of 2,4-Dichloro-3-nitrophenol Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics