《Facile One-Pot Access to α-Diazo-β-ketosulfones from Sulfonyl Chlorides and α-Haloketones》 was published in Synthesis in 2020. These research results belong to Dar’in, Dmitry; Kantin, Grigory; Bakulina, Olga; Krasavin, Mikhail. SDS of cas: 16629-19-9 The article mentions the following:
A convenient one-pot approach to the preparation of α-diazo-β-ketosulfones R1SO2C(=N2)C(O)R2 [R1 = Me, cyclohexyl, Ph, etc.; R2 = Me, Ph, 4-FC6H4, etc.] from sulfonyl chlorides was described. It involved the conversion of sulfonyl chloride to sodium sulfinate, alkylation of latter with α-haloketones followed by diazo transfer using ‘sulfonyl-azide-free’ (SAFE) protocol in aqueous medium. The simple and expedient method relied on readily available starting materials and provided facile access to a wide variety of valuable diazo reagents for organic synthesis. After reading the article, we found that the author used Thiophene-2-sulfonyl chloride(cas: 16629-19-9SDS of cas: 16629-19-9)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. SDS of cas: 16629-19-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics