Ding, Ran; Fu, Jian-Ming; Tian, Hai-Yu; Chen, Nian-Shou; Liu, Lei; Guo, Yu; Wang, Pei-Long published their research in New Journal of Chemistry in 2021. The article was titled 《Sulfonyl radical-induced regioselective cyclization of 3-aza-1,5-enynes with sulfonyl chlorides to produce 1,2-dihydropyridines by copper catalysis》.Recommanded Product: Thiophene-2-sulfonyl chloride The article contains the following contents:
A Cu-catalyzed regioselective cyclization of 3-aza-1,5-enynes with sulfonyl chlorides for the synthesis of 1,2-dihydropyridines I [R = 4-MeC6H4, 3-ClC6H4, 2-thienyl, etc.; R1 = Me, Ph, 3-MeC6H4, 4-MeOC6H4, 2-NCC6H4, 2-thienyl; R2 = H, Me, Et; R3 = Ph, 4-BrC6H4, 2-naphthyl, etc.] was described. This present method provided a new pathway for the construction of 1,2-dihydropyridines from 3-aza-1,5-enynes in reasonable yields and an alternative method for the synthesis of 3-functionalized multi-substituted pyridines. In the experimental materials used by the author, we found Thiophene-2-sulfonyl chloride(cas: 16629-19-9Recommanded Product: Thiophene-2-sulfonyl chloride)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Recommanded Product: Thiophene-2-sulfonyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics