Guo, Haichang; Zheng, Renhua; Jiang, Huajiang; Xu, Zhenyuan; Xia, Aibao published their research in BMC Chemistry on December 31 ,2019. The article was titled 《Preparation of sub-microspherical Fe3O4@PDA-Pd NPs catalyst and application in catalytic hydroreduction reaction of halogenated aromatic nitro compounds to prepare halogenated aromatic amines》.Safety of 3-Chloro-4-fluoronitrobenzene The article contains the following contents:
A promising method for preparation of the superparamagnetic and strongly magnetic Fe3O4@PDA core-shell sub-microsphere-supported nano-palladium catalyst for catalyzing the hydrogenation reduction of halogenated aromatic nitro compds was reported. The catalyst showed a high selectivity of greater than 96% and effectively inhibited the occurrence of the side reactions of dehalogenation and C-N coupling. The optimum condition of the hydroredn. reaction was when THF is used as solvent and the reaction occurred at 50° for 5 h. The selectivity of the chlorinated aromatic amine and the fluorinated aromatic amine products exceeded 99% and the yield exceeds 90%. Only a small amount of dehalogenated products and C-N coupling byproducts were produced in the brominated aromatic compound and the iodinated aromatic compound In the experiment, the researchers used many compounds, for example, 3-Chloro-4-fluoronitrobenzene(cas: 350-30-1Safety of 3-Chloro-4-fluoronitrobenzene)
3-Chloro-4-fluoronitrobenzene(cas: 350-30-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Organochlorine compounds have wide use in many applications, though some are of profound environmental concern, with TCDD being one of the most notorious.Safety of 3-Chloro-4-fluoronitrobenzene
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics