《Through-Space Polar-π Interactions in 2,6-Diarylthiophenols》 was published in ChemPhysChem in 2020. These research results belong to Jian, Jie; Poater, Jordi; Hammink, Roel; Tinnemans, Paul; McKenzie, Christine J.; Bickelhaupt, F. Matthias; Mecinovic, Jasmin. Related Products of 768-35-4 The article mentions the following:
Mol. recognition between polar groups and aromatic mols. is fundamentally important to rational drug design. Although it has been well established that many polar functionalities interact with electron-rich aromatic residues through energetically favorable polar-π interactions, there is a limited understanding of the association between thiols and aromatic systems. Herein we report phys.-organic chem. studies on 2,6-diarylthiophenols that possess the central thiophenol ring and two flanking aromatic rings with tunable electronic properties caused by substituents at distant para position. Hammett anal. revealed that pKa values and proton affinities correlate well with Hammett sigma values of substituents. Addnl. energy decomposition anal. supported the conclusion that both through-space SH-π interactions and S–π interactions contribute to intramol. stabilization of 2,6-diarylthiophenols. In addition to this study using (3-Fluorophenyl)boronic acid, there are many other studies that have used (3-Fluorophenyl)boronic acid(cas: 768-35-4Related Products of 768-35-4) was used in this study.
(3-Fluorophenyl)boronic acid(cas: 768-35-4) can be used to make novel liquid crystalline fluorobiphenylcyclohexenes and difluoroterphenyls by palladium-catalyzed cross-couplings also used in the synthesis of o-phenylphenols as potent leukotriene B4 receptor agonists.Related Products of 768-35-4
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics