Kotha, Sambasivarao; Pulletikurti, Sunil; Fatma, Ambareen; Dhangar, Gopal; Naidu, Gonna Somu published an article in 2021. The article was titled 《Synthesis of Polycycles and Oxacycles via Tandem Metathesis of endo -Norbornene Derivatives》, and you may find the article in Synthesis.Computed Properties of C43H72Cl2P2Ru The information in the text is summarized as follows:
Here, the presence of a carbonyl group at C7 position prevents the olefin metathesis of endo-norbornene derivatives due to complexation of the metal alkylidene has been demonstrated. Time-dependent NMR studies showed the presence of new proton signals in the metal alkylidene region, which indicate the formation of metal complex with the carbonyl group of the substrate. These observations were further proved by ESI-MS anal. Whereas computational studies showed that the catalyst was interacting with the C7 carbonyl group and aligned perpendicular to that of norbornene olefin. These endo-keto norbornene derivatives were reduced to hydroxyl derivatives diastereoselectively. Ring-rearrangement metathesis (RRM) of these hydroxyl derivatives, produced the [6/5/6], and [5/6/5] carbo-tricyclic cores of natural products in one step. Whereas the RRM of O-allyl derivatives, delivered the oxa-tricyclic compounds in a single step with excellent yields. The results came from multiple reactions, including the reaction of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Computed Properties of C43H72Cl2P2Ru)
Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Computed Properties of C43H72Cl2P2Ru
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics