In 2019,RSC Advances included an article by Li, Chen; Chen, Xian; Bao, Rui-Peng; Li, Dong-Li; Zhang, Kun; Wang, Dong-Hui. Category: chlorides-buliding-blocks. The article was titled 《Ir(III)-catalyzed thioether directed arene C-H alkenylation》. The information in the text is summarized as follows:
In this study, an Ir(III)-catalyzed thioether directed alkenylation of arene C-H bonds under mild reaction conditions has been described. The selectivity for mono- or di-alkenylation is controlled by the concentration of alkene and oxidant loading. Various functional groups are tolerated, and moderate to good yields of alkenylated products are achieved. In the experiment, the researchers used many compounds, for example, 1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7Category: chlorides-buliding-blocks)
1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7) may be used to synthesize 1-(4-chlorobenzyl)-2-(pyrrolidin-1-yl-methyl)-1H-benzimidazole dihydrochloride.Category: chlorides-buliding-blocks It can be synthesized by reacting 4-chlorobenzyl alcohol with bromodimethylsulfonium bromide (BDMS) It can also be synthesized by refluxing a mixture of 4-chlorobenzaldehyde, chlorotrimethylsilane, 1,1,3,3-tetramethyldisiloxane and lithium bromide.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics