Li, Yaru; Ren, Pengju; Zhang, Dongsheng; Qiao, Wei; Wang, Dan; Yang, Xiaoqin; Wen, Xiaodong; Rummeli, Mark H.; Niemantsverdriet, Hans; Lewis, James P.; Besenbacher, Flemming; Xiang, Hongwei; Li, Yongwang; Su, Ren published their research in ACS Catalysis in 2021. The article was titled 《Rationally Designed Metal Cocatalyst for Selective Photosynthesis of Bibenzyls via Dehalogenative C-C Homocoupling》.Category: chlorides-buliding-blocks The article contains the following contents:
Cu is a promising candidate to promote the coupling of aromatic halides RCH2X (Ph, 3,4-dimethylphenyl, 4-chloro-3-methoxyphenyl, etc.; X = Br, Cl) due to the optimized adsorption energy of the reaction intermediates (benzyl radical and Br atom) over a series of transition metals. The Cu-modified TiO2 shows a remarkable apparent quantum efficiency (15%) and a great tolerance of harsh reaction conditions for the homocoupling of benzyl bromides into bibenzyls R(CH2)2R under UV irradiation The low-cost photocatalyst also shows high performance upon scaling-up and selective coupling of a series of benzyl bromide derivatives, demonstrating the heterogeneous photocatalytic C-C coupling as an attractive process for applications. Addnl., the design strategy can be applied to modify other photocatalysts (i.e., g-C3N4) to realize the C-C coupling of benzyl bromide under visible light. After reading the article, we found that the author used 1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7Category: chlorides-buliding-blocks)
1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7) may be used to synthesize 1-(4-chlorobenzyl)-2-(pyrrolidin-1-yl-methyl)-1H-benzimidazole dihydrochloride.Category: chlorides-buliding-blocks It can be synthesized by reacting 4-chlorobenzyl alcohol with bromodimethylsulfonium bromide (BDMS) It can also be synthesized by refluxing a mixture of 4-chlorobenzaldehyde, chlorotrimethylsilane, 1,1,3,3-tetramethyldisiloxane and lithium bromide.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics