Liu, Zhi-Yun; Cook, Silas P. published an article in 2022. The article was titled 《Directed Ni-Catalyzed Reductive Arylation of Aliphatic C-H Bonds》, and you may find the article in Organic Letters.Recommanded Product: Methyl 2-chloro-2-oxoacetate The information in the text is summarized as follows:
Herein, authors describe a nickel-catalyzed reductive arylation of remote C(sp3)-H bonds with aryl electrophiles. The reaction targets secondary and tertiary C(sp3)-H bonds to deliver all-carbon quaternary centers. The success of this method relies on a novel amidyl radical precursor that tolerates reducing conditions-O-oxalate hydroxamic acid esters. After reading the article, we found that the author used Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3Recommanded Product: Methyl 2-chloro-2-oxoacetate)
Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3) belongs to acyl chlorides. In the laboratory, acyl chlorides are generally prepared by treating carboxylic acids with thionyl chloride (SOCl2). The reaction is catalyzed by dimethylformamide and other additives.Recommanded Product: Methyl 2-chloro-2-oxoacetate
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics