Computed Properties of C43H72Cl2P2RuIn 2020 ,《Domino Relay Olefin Metathesis of Triallyl Oxindole and Indole Precursors to Access Cyclic Indoxyls and Carbazoles》 was published in ChemCatChem. The article was written by Mandal, Tirtha; Dhara, Kalyan; Parui, Nabin; Dash, Jyotirmayee. The article contains the following contents:
Domino relay metathesis sequences using triallyl 3-oxindoles I (R = H, Cl, OMe) and indoles 1,2,3-tris(prop-2-en-1-yl)-1H-indole and 5-chloro-1,2,3-tris(prop-2-en-1-yl)-1H-indole precursor to access C2-quaternary cyclic pseudooxindoles II and carbazole ring systems like 9-(2-propen-1-yl)-9H-carbazole and 3-chloro-9-(2-propen-1-yl)-9H-carbazole have been described. Triallyl 3-oxindoles I undergo domino ring closing metathesis (RCM) and cross metathesis (CM) to provide C2-spirocyclic 3-oxindoles II. Intriguingly, a catalyst specific relay metathesis sequence involving ring closing-ring opening-ring closing and cross metathesis (RC-RO-RC-CM) of these trienes I is established to provide fused bicyclic indoxyl dimers III in high yields. Further, the CM of indoxyl dimer III (R = Cl) with Me acrylate affords a new class of fused monomeric 3-oxindole derivative like Me 4-(8-chloro-10-oxo-1H,4H,10H,10aH-pyrido[1,2-a]indol-10a-yl)but-2-enoate. Moreover, a domino RCM-CM process of triallyl indoles is demonstrated, enabling a quick access to dihydro-carbazoles like 9-(prop-2-en-1-yl)-4,9-dihydro-1H-carbazole, 6-chloro-9-(prop-2-en-1-yl)-4,9-dihydro-1H-carbazole and carbazoles. After reading the article, we found that the author used Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Computed Properties of C43H72Cl2P2Ru)
Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Computed Properties of C43H72Cl2P2Ru
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics