In 1957,Yakugaku Zasshi included an article by Matsuura, Shin; Matsuura, Akira. Recommanded Product: 56966-48-4. The article was titled 《Synthesis of 2′-hydroxy-3′ (and 5′)-acetyl-4,4′-dimethoxychalcone》. The information in the text is summarized as follows:
2,4-HO(MeO)C6H3COCH:CH6C6H4OMe-4 (I) (2.8 g.), 1 g. AcCl,40 ml. PhNO2, and 1.5 g. AlCl3, let stand 2 days, let stand 2 days with an addnl. 1 g. AlCl3 the product decomposed with HCl, steam distilled, the residue extracted with C6H6, the C6H6 removed, and the residue in 150 ml. EtOH evaporated to one-half separated 0.48 g. 3′-Ac derivative (II) of I, needles, m. 145.5°. The above reaction at 15° yielded 0.3 g. 5′-Ac derivative (III) of I, needles, m. 171.5°. Reaction of 5 g. 2,4-AcO(MeO)C6H3COCH: CHC6H4OMe-4 (IV), 4 g. AlCl3, and 50 ml. PhNO2 yielded 0.1 g. II, m. 145.5°. Condensation of 1 g. 2,4-diacetyl-resorcinol mono-Me ether and 1 g. p-MeOC6H6CHO (V) in 10 ml. EtOH and 4 ml. 50% KOH gave 1.6 g. 2′-hydroxy-3′-( 4-methoxycinnamoyl)-4,4′-dimethoxychalcone (VI), needles, m. 171° (from dilute AcOH). Condensation of 0.1 g. II and 0.2 g. V in 5 ml. EtOH and 1 g. 50% KOH yielded 0.07 g. VI, m. 171°. Similarly, 0.1 g. III and 0.5 g. V in 5 ml. EtOH and 1 g. 50% KOH gave 0.12 g. 2′-hydroxy-4,4′-dimethoxy-5′-(4-methoxycinnamoyl)chalcone, m. 190°. The experimental process involved the reaction of 2-Amino-2,4-dichlorodiphenyl ether(cas: 56966-48-4Recommanded Product: 56966-48-4)
2-Amino-2,4-dichlorodiphenyl ether(cas: 56966-48-4) belongs to anime. Examples of direct uses of amines and their salts are as corrosion inhibitors in boilers and in lubricating oils (morpholine), as antioxidants for rubber and roofing asphalt (diarylamines), as stabilizers for cellulose nitrate explosives (diphenylamine), as protectants against damage from gamma radiation (diarylamines), as developers in photography (aromatic diamines), as flotation agents in mining, as anticling and waterproofing agents for textiles, as fabric softeners, in paper coating, and for solubilizing herbicides.Recommanded Product: 56966-48-4
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics