Morrill, Charlotte; Gillespie, James E.; Phipps, Robert J. published the artcile< An Aminative Rearrangement of O-(Arenesulfonyl)hydroxylamines: Facile Access to ortho-Sulfonyl Anilines>, Name: 3-Chloro-4-methylbenzene-1-sulfonyl chloride, the main research area is ortho sulfonyl aniline regioselective preparation; arenesulfonyl hydroxylamine ortho aminative rearrangement ferrous sulfate catalyst; Arene Amination; Ion-Pairing; Non-Covalent Interactions; Radical Reactions; Regioselectivity.
The discovery of an aromatic rearrangement reaction of O-(arenesulfonyl)hydroxylamines which lead directly to ortho-aminoarylsulfonic acids and ortho-aminobenzenemethanesulfonic acids through formation of a new C-N bond with excellent levels of regiocontrol for the ortho position(s) over all others was reported. The rearrangement was proceeding through an intermol. mechanism and proposed that the regiocontrol observed was the result of attractive non-covalent interactions occurring during the C-N bond-forming step. Importantly, this method was complementary to classical aniline sulfonation in terms of the variously substituted regioisomers that could be obtained and it was also applicable to O-(benzylsulfonyl) hydroxylamines.
Angewandte Chemie, International Edition published new progress about Amination catalysts. 42413-03-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H6Cl2O2S, Name: 3-Chloro-4-methylbenzene-1-sulfonyl chloride.
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics