Reddy, Chada Raji; Kolgave, Dattahari H.; Subbarao, Muppidi; Aila, Mounika; Prajapti, Santosh Kumar published the artcile< Ag-Catalyzed Oxidative ipso-Cyclization via Decarboxylative Acylation/Alkylation: Access to 3-Acyl/Alkyl-spiro[4.5]trienones>, Quality Control of 3240-10-6, the main research area is spirotrienone preparation; pyrroloquinoline dione preparation; arylpropiolamide acid tandem decarboxylative acylation alkylation cyclization silver catalyst.
A strategy to functionalized spiro[4.5]trienones I [R = Ph, 2-thienyl, 1-naphthyl, etc.; R1 = Me, Bn, Ts, etc.; R2 = H, 7-Me, 7-F, etc.; R3 = Me, C(O)Me, C(O)Ph, etc.] by domino silver-catalyzed decarboxylative acylation or alkylation/ipso-cyclization of N-arylpropiolamides with α-keto acids/alkyl carboxylic acids was presented. This transformation offered a wide range of substituted 3-acyl/alkyl-spiro[4.5]trienones in high yields with a broad substrate scope. The approach was further extended to access fused tricyclic frameworks, 6,7-dihydro-3H-pyrrolo[2,1-j]quinoline-3,9(5H)-diones II [R4 = Ph, 4-ClC6H4, 4-AcC6H4; R5 = t-Bu, C(O)Et, C(O)Ph, etc.].
Organic Letters published new progress about Acylation. 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, Quality Control of 3240-10-6.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics