Rogers, David A.; Hopkins, Megan D.; Rajagopal, Nitya; Varshney, Dhruv; Howard, Haley A.; LeBlanc, Gabriel; Lamar, Angus A. published the artcile< U.S. Food and Drug Administration-Certified Food Dyes as Organocatalysts in the Visible Light-Promoted Chlorination of Aromatics and Heteroaromatics>, Product Details of C4H4ClNO2, the main research area is aryl chloride regioselective preparation; arene chlorosuccinimide visible light promoted chlorination food dye organocatalyst.
Seven FDA-certified food dyes were investigated as organocatalysts. As a result, Fast Green FCF and Brilliant Blue FCF were discovered as catalysts for the chlorination of a wide range of arenes and heteroarenes in moderate to excellent yields and high regioselectivity. Mechanistic investigations of the sep. systems indicated that different modes of activation are in operation, with Fast Green FCF being a light-promoted photoredox catalyst that was facilitating a one-electron oxidation of N-chlorosuccinimide (NCS) and Brilliant Blue FCF serving as a chlorine-transfer catalyst in its sulfonphthalein form with 1,3-dichloro-5,5-dimethylhydantoin (DCDMH) as stoichiometric chlorine source. Dearomatization of naphthol and indole substrates was observed in some examples using the Brilliant Blue/DCDMH system.
ACS Omega published new progress about Aromatic hydrocarbons Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 128-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C4H4ClNO2, Product Details of C4H4ClNO2.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics