Shi, Jun-Bin; Bu, Qingqing; Liu, Bin-Yuan; Dai, Bin; Liu, Ning published the artcile< Organocatalytic Strategy for the Fixation of CO2 via Carboxylation of Terminal Alkynes>, Quality Control of 3240-10-6, the main research area is propiolic acid preparation; terminal alkyne carbon dioxide carboxylation organocatalyst.
An organocatalytic strategy for the direct carboxylation of terminal alkynes with CO2 had been developed. The combined use of a bifunctional organocatalyst and Cs2CO3 resulted in a robust catalytic system for the preparation of a range of propiolic acid derivatives RC≡CCOOH [R = t-Bu, Ph, 2-thienyl, etc.] in high yields with broad substrate scope using CO2 at atm. pressure under mild temperatures (60°C). This work had demonstrated that this organocatalytic method offered a competitive alternative to metal catalysis for the carboxylation of terminal alkynes and CO2. In addition, this protocol was suitable for the three-component carboxylation of terminal alkynes, alkyl halides and CO2.
Journal of Organic Chemistry published new progress about Alkynes, α- Role: RCT (Reactant), RACT (Reactant or Reagent). 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, Quality Control of 3240-10-6.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics