Swarts, Henk J.; Verhagen, Frank J. M.; Field, Jim A.; Wijnberg, Joannes B. P. A. published an article in Phytochemistry. The title of the article was 《Novel chlorometabolites produced by Bjerkandera species》.COA of Formula: C8H6Cl2O3 The author mentioned the following in the article:
The EtOAc extract from the extracellular fluid of the mycelium of Bjerkandera sp. BOS55 contained four novel chlorinated benzoic acid derivatives, i.e. 3-chloro-4-hydroxybenzoic acid, 3,5-dichloro-4-hydroxy-benzoic acid, Me 3,5-dichloro-4-hydroxybenzoate and Me 3,5-dichloro-p-anisate. 3-Chloro-4-hydroxybenzoic acid was also produced by B. adusta. In addition to this study using 3,5-Dichloro-4-methoxybenzoic acid, there are many other studies that have used 3,5-Dichloro-4-methoxybenzoic acid(cas: 37908-97-7COA of Formula: C8H6Cl2O3) was used in this study.
3,5-Dichloro-4-methoxybenzoic acid(cas: 37908-97-7) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. COA of Formula: C8H6Cl2O3 However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics