In 2019,RSC Advances included an article by Xiao, Jing; Ma, Yonghao; Wu, Xiaofang; Gao, Jing; Tang, Zilong; Han, Li-Biao. SDS of cas: 622-95-7. The article was titled 《Phosphonic acid mediated practical dehalogenation and benzylation with benzyl halides》. The information in the text is summarized as follows:
For the first time, by using H3PO3/I2 system, various benzyl chlorides and bromides RCH2X (R = C6H5, 4-O2NC6H4, 1-naphthyl, etc.; X = Cl, Br) were dehalogenated successfully. In the presence of H3PO3, benzyl halides underwent electrophilic substitution reactions with electron-rich arenes, leading to a broad range of diarylmethanes RCH2R1 (R1 = C6H5, 2,4,6-(CH3)3C6H2, 4-CH3OC6H4, etc.) in good yields. These transformations feature green, cheap reducing reagents and metal-free conditions. In the experiment, the researchers used 1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7SDS of cas: 622-95-7)
1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7) is a useful reagent for the preparation of panicinotam derivatives for use as anti-inflammatory agents or immunomodulators.SDS of cas: 622-95-7 It can be synthesized by reacting 4-chlorobenzyl alcohol with bromodimethylsulfonium bromide (BDMS) It can also be synthesized by refluxing a mixture of 4-chlorobenzaldehyde, chlorotrimethylsilane, 1,1,3,3-tetramethyldisiloxane and lithium bromide.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics