The author of 《Deracemization of axially chiral nicotinamides by dynamic salt formation with enantiopure dibenzoyltartaric acid (DBTA)》 were Yagishita, Fumitoshi; Kamataki, Norifumi; Okamoto, Kazuma; Kanno, Shota; Mino, Takashi; Masu, Hyuma; Sakamoto, Masami. And the article was published in Molecules in 2013. Category: chlorides-buliding-blocks The author mentioned the following in the article:
The dynamic atroposelective resolution of chiral salts derived from oily racemic nicotinamides (RS)-I (R = pyrrolidino, piperidino, morpholino) and enantiopure dibenzoyltartaric acid (DBTA) was achieved by crystallization The absolute structures of the axially chiral nicotinamides were determined by X-ray structural anal. The chirality could be controlled by the selection of enantiopure DBTA as a chiral auxiliary. The axial chirality generated by dynamic salt formation was retained for a long period after dissolving the chiral salt in solution even after removal of the chiral acid. The rate of racemization of nicotinamides could be controlled based on the temperature and solvent properties, and that of the salts were prolonged compared to free nicotinamides, as the mol. structure of the pyridinium ion in the salts was different from that of acid-free nicotinamides. In the experimental materials used by the author, we found 2-Chloro-4,6-dimethylnicotinic acid(cas: 66662-48-4Category: chlorides-buliding-blocks)
2-Chloro-4,6-dimethylnicotinic acid(cas: 66662-48-4) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Category: chlorides-buliding-blocks
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics