Formula: C11H13ClO2On June 2, 2017, Zhang, Hongwei; Muniz, Kilian published an article in ACS Catalysis. The article was 《Selective Piperidine Synthesis Exploiting Iodine-Catalyzed Csp3-H Amination under Visible Light》. The article mentions the following:
A route to selective piperidine formation through intramol. catalytic Csp3-H amination is described. This hydrocarbon amination reaction employs a homogeneous iodine catalyst derived from halogen coordination between mol. iodine and a terminal oxidant. It relies on visible light initiation and proceeds within two catalytic cycles that comprise a radical C-H functionalization and an iodine-catalyzed C-N bond formation. The protocol is demonstrated for a total of 30 applications. In addition to this study using Ethyl 3-(4-chlorophenyl)propanoate, there are many other studies that have used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Formula: C11H13ClO2) was used in this study.
Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Formula: C11H13ClO2 Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics