Zhang, Muliang; Yuan, Xiang-Ai; Zhu, Chengjian; Xie, Jin published the artcile< Deoxygenative Deuteration of Carboxylic Acids with D2O>, Application of C10H9ClO2, the main research area is deuterated aryl alkyl aldehyde chemoselective preparation; chemoselective photochem reduction deuteration aryl alkyl aldehyde iridium photocatalyst; phenylphosphine phenylphosphinite oxygen acceptor chemoselective deuteration reduction aldehyde; aldehydes; carboxylic acids; deoxygenation; deuteration; synergistic catalysis.
C1-Deuterated aryl and alkyl aldehydes such as 4-PhC6H4CDO and PhCH2CH2CDO were prepared chemoselectively with 58-96% deuterium incorporation by reduction of aromatic and aliphatic carboxylic acids using iridium photocatalysts, either Ph3P or Ph2OEt as an oxygen acceptor, 2,4,6-i-Pr3C6H2SH as a hydrogen atom donor, and using D2O as an inexpensive deuterium source. The method was used for the preparation of deuterated derivatives of pharmaceuticals and natural products containing aromatic carboxylic acid moieties. The method was also used for chemoselective reduction of aryl and alkyl carboxylic acids to the corresponding aldehydes using H2O as a hydrogen atom source.
Angewandte Chemie, International Edition published new progress about Acidity. 90940-40-2 belongs to class chlorides-buliding-blocks, and the molecular formula is C10H9ClO2, Application of C10H9ClO2.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics