Zhang, Wei; Zheng, Suqing; Liu, Na; Werness, Jenny B.; Guzei, Ilia A.; Tang, Weiping published the artcile< Enantioselective bromolactonization of conjugated (Z)-enynes>, Synthetic Route of 22717-55-1, the main research area is lactone derivative asym preparation; conjugated enyne preparation bromolactonization cinchona.
A catalytic enantioselective syn-1,4-bromolactonization of conjugated (Z)-enynes was reported. Diastereomeric ratios >20:1 and up to 99% enantiomeric excesses were observed Di-, tri-, and tetra-substituted bromoallenes were prepared together with lactone heterocycles efficiently and stereoselectively. Preliminary investigations suggest that the chiral catalyst may serve as a bifunctional reagent by interacting with both a carboxylic acid nucleophile and NBS electrophile.
Journal of the American Chemical Society published new progress about Alkenynes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 22717-55-1 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO3, Synthetic Route of 22717-55-1.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics