In 2022,Zhu, Wenjuan; Xi, Hui; Jiao, Wenyang; Huang, Lihua; Wang, Lianjie; Wu, Junliang published an article in Organic Letters. The title of the article was 《Difunctionalization of gem-Difluoroalkenes via Photoredox Catalysis: Synthesis of Diverse α,α-Difluoromethyl-β-alkoxysulfones》.Name: Thiophene-2-sulfonyl chloride The author mentioned the following in the article:
Visible-light-promoted R1CH=CF2 (R1 = 2H-1,3-benzodioxol-5-yl, 3-bromo-4-methoxyphenyl, 4-(benzyloxy)phenyl, etc.) using sulfonyl chlorides R2S(O)OCl (R2 = 4-tert-butylphenyl, naphthalen-1-yl, thiophen-2-yl, cyclopropyl, etc.) and alcs. R3OH (R3 = Me, Bn, i-Pr, etc.) has been developed. The reaction exhibits a relatively broad substrate scope with excellent functional group compatibility. This synthesis method includes an atom transfer radical addition-like process. The products R1CH(O)R2CF2S(O)OR3 can be used as platform mols. for further modification. In the experimental materials used by the author, we found Thiophene-2-sulfonyl chloride(cas: 16629-19-9Name: Thiophene-2-sulfonyl chloride)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Name: Thiophene-2-sulfonyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics