The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Application In Synthesis of 2905-24-0.
Hervieu, Cedric;Kirillova, Mariia S.;Suarez, Tatiana;Muller, Marco;Merino, Estibaliz;Nevado, Cristina research published 《 Asymmetric, visible light-mediated radical sulfinyl-Smiles rearrangement to access all-carbon quaternary stereocentres》, the research content is summarized as follows. The asym. construction of all-carbon quaternary centers within acyclic settings represents a long-standing challenge for synthetic chemists. Alongside polar and radical methods, rearrangement reactions represent an attractive platform, but still broadly applicable methods are in high demand. Here we report an asym., radical sulfinyl-Smiles rearrangement to access acyclic amides that bear an α-all-carbon quaternary center. Our strategy uses enantioenriched N-arylsulfinyl acrylamides such as I as acceptors for a variety of radicals produced in situ under mild photoredox conditions. The sulfinamido group not only directs the 1,4-migration of the aryl moiety onto the α-carbon of the amide, which thus governs its absolute configuration, but also functions as a traceless chiral auxiliary. The amides obtained in this multicomponent process such as II are prevalent in pharmaceuticals, agrochems. and bioactive natural products, and can be transformed into valuable chiral α,α-disubstituted acids, oxindoles as well as into β,β-disubstituted amines, highlighting the synthetic potential of this transformation.
2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., Application In Synthesis of 2905-24-0
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics