Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. SDS of cas: 6334-18-5.
Kumar, Sunil;Choudhary, Mukesh research published ã?Molecular docking, X-ray crystallography, Hirshfeld surface and computational studies of N-((2,3-dichlorophenyl)(ethoxy)methyl)-2-methoxy-4-nitrobenzenamineã? the research content is summarized as follows. In this study, we report the synthesis, characterization and theor. study of an organic compound namely N-((2,3-dichlorophenyl)(ethoxy)methyl)-2-methoxy-4-nitrobenzenamine (L) as potential drug candidate against SARS-CoV-2 main protease. Structural and Hirshfeld surface anal. was carried out on the organic compound (L). The potential application was also assessed through mol. docking and 3-D visualizations of intermol. interactions with two very important crucial proteins of SARS-CoV-2 (MPro-7C6U & 7C6S). Mol. docking calculations exhibited high binding energy and inhibition constant of -7.4 kcal/mol and 2.413 μM with SARS-CoV-2 MPro. Besides this, an ADMET prediction was also studied. This study provides an alternative and viable therapeutic agent for SARS-CoV-2 virus.
SDS of cas: 6334-18-5, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., 6334-18-5.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics