On September 16, 2016, Zhang, Ziqian; Li, Yi; He, Haihong; Qian, Xuhong; Yang, Youjun published an article.SDS of cas: 99-60-5 The title of the article was Mild Chemotriggered Generation of a Fluorophore-Tethered Diazoalkane Species via Smiles Rearrangement. And the article contained the following:
Nitrosamino naphthalenedicarboximide I and a related disulfide underwent Smiles rearrangement in the presence of nucleophiles to generate diazo compounds in situ under mild conditions (in aqueous buffer or MeCN at ambient temperature); reaction with nucleophiles such as carboxylic acids RCO2H [R = Me, i-Pr, Me(CH2)10, (E,E)-MeCH:CHCH:CH, Me2C:CH, 1-adamantyl, Ph, 3-HOC6H4, 2-HOC6H4, 2-Ph2PC6H4, 4-MeC6H4, 4-BrC6H4, 4-O2NC6H4, 2-Cl-4-O2NC6H3, 4-Et2NC6H4, 1-naphthyl] or dimethylamine or activation with glutathione yielded fluorescent products such as acyloxyethylthio naphthalenedicarboximides II [R = Me, i-Pr, Me(CH2)10, (E,E)-MeCH:CHCH:CH, Me2C:CH, 1-adamantyl, Ph, 3-HOC6H4, 2-HOC6H4, 2-Ph2PC6H4, 4-MeC6H4, 4-BrC6H4, 4-O2NC6H4, 2-Cl-4-O2NC6H3, 4-Et2NC6H4, 1-naphthyl] in 16-45% yields. The structure of I was determined by X-ray crystallog. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).SDS of cas: 99-60-5
The Article related to nitrosamino naphthalenedicarboximide preparation rearrangement nucleophile, acyloxyethylthio naphthalenedicarboximide preparation fluorescence, diazo compound formation smiles rearrangement nitrosamino naphthalenedicarboximide, carboxylic acid reaction in situ generated diazo compound, acetylthioethyl nitrosamino naphthalenedicarboximide mol crystal structure and other aspects.SDS of cas: 99-60-5
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