Chloride substituents modify the physical properties of organic compounds in several ways. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Electric Literature of 2905-24-0.
Michelet, Bastien;Castelli, Ugo;Appert, Emeline;Boucher, Maude;Vitse, Kassandra;Marrot, Jerome;Guillard, Jerome;Martin-Mingot, Agnes;Thibaudeau, Sebastien research published 《 Access to Optically Pure Benzosultams by Superelectrophilic Activation》, the research content is summarized as follows. Through superacid activation, N-(arenesulfonyl)-amino alcs. derived from readily available ephedrines or amino acids undergo an intramol. Friedel-Crafts reaction to afford enantiopure benzosultams bearing two adjacent stereocenters in high yields with fully controlled diastereoselectivity. Low-temperature NMR spectroscopy demonstrated the crucial role played by the conformationally restricted chiral dicationic intermediates.
2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., Electric Literature of 2905-24-0
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics