Rao, Wei-Hao team published research in Journal of Organic Chemistry in 2021 | 2905-24-0

2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., Formula: C6H4BrClO2S

Chloride substituents modify the physical properties of organic compounds in several ways. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Formula: C6H4BrClO2S.

Rao, Wei-Hao;Li, Qi;Chen, Fang-Yuan;Jiang, Li-Li;Xu, Pan;Deng, Xue-Wan;Li, Ming;Zou, Guo-Dong;Cao, Xinhua research published 《 Visible-Light Photoredox-Catalyzed Sulfonyl Lactonization of Alkenoic Acids with Sulfonyl Chlorides for Sulfonyl Lactone Synthesis》, the research content is summarized as follows. A visible-light photoredox-catalyzed sulfonyl lactonization of unsaturated carboxylic acids RC(=CH2)R1 (R = 2-carboxyphenyl, 2-carboxyethyl, (1-carboxycyclopentyl)methyl, etc.; R1 = Me, Ph, 4-fluorophenyl, etc.) with sulfonyl chlorides R2S(O)OCl (R2 = n-Bu, tosyl, naphthalen-1-yl, cyclopropyl, etc.) is described. This reaction features good functional group tolerance and a broad substrate scope, providing a simple and efficient protocol to access a wide range of sulfonyl lactones e.g., 3-(tosylmethyl)-isobenzofuran-1(3H)-one in high to excellent yields. Preliminary mechanistic investigations suggested that a free-radical pathway should be involved in the process.

2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., Formula: C6H4BrClO2S

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics