The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 3900-89-8, formula is C6H6BClO2, Name is (2-Chlorophenyl)boronic acid. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Product Details of C6H6BClO2.
Sontakke, Geetanjali S.;Shukla, Rahul K.;Volla, Chandra M. R. research published 《 Rh(I)-Catalyzed Decarboxylative Arylation of Alkynyl Cyclic Carbonates: Divergent Access to Substituted α-Allenols and 1,3-Butadienes》, the research content is summarized as follows. Rh(I)-catalyzed decarboxylative arylation of alkynyl cyclic carbonates I (R1 = Ph, naphthalen-2-yl, thiophen-2-yl, etc; R2 = H, Ph, n-Bu, cyclopropyl, etc.) using com. available and low-toxic aryl boronic acids ArB(OH)2 (Ar = 4-methoxyphenyl, 3-chlorophenyl, thiophen-2-yl, etc.) has been disclosed. Depending on the nature of the cyclic carbonates, the methodol. provides a straightforward platform to access either substituted 2,3-allenols R1C(CH2OH)C=C=C(R2)Ar (II)/1,3-butadiene derivatives ArCH=C(Ar)C(=CH)R1 (II). Internal alkynyl cyclic carbonates I undergo monoarylation to conveniently afford 2,3-allenols II with high syn-selectivity for the aryl and hydroxy groups. The terminal alkynyl carbonates I led to the formation of diarylated 1,3-butadiene derivatives III having cis-configuration for the two aryl groups via allenyl rhodium(I)alkoxide intermediate. The compatibility of various functional groups allowed to develop a library of diversely functionalized scaffolds with excellent regioselectivity in good yields. Late-stage transformation of a series of natural products highlights the wide applicability of the arylation process. Addnl., scale-up experiments and downstream transformations of α-allenol derivatives into other valuable heterocycles illustrate the efficacy of the protocol.
Product Details of C6H6BClO2, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., 3900-89-8.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics